Jusqu'à maintenant, l'équipe de recherche a réalisé :

plusieurs articles, des chapitres de livre et la rédaction d'un livre.

Publications

Récents articles revus et publiés
  • Jia, N., Rosella, E., Juere, E., Pouliot, R., Kleitz, F. et Greener, J. (2020) A microfluidic approach to micromembrane synthesis for complex release profiles of nanocarriers. Lab Chip. 20, 6, 1066-1071.
  • Bélanger, A., Grenier, A., Simard, F., Gendreau, I., Pichette, A., Legault, J. et Pouliot, R. (2020) Dihydrochalcone Derivatives from Populus balsamifera L. Buds for the Treatment of Psoriasis. Int J Mol Sci. 21, 256; doi:10.3390/ijms21010256.
  • Zhang, H., Carnevale, G., Polese, B., Simard, M., Thurairajah, B., Khan, N., Gentile, M.E., Fontes, G., Vinh, D.C., Pouliot, R., King, I.L. (2019) CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota. Cell Rep. 8, 29(2):391-405.e5; doi: 10.1016/j.celrep.2019.09.003.
  • Simard, M., Julien, P., Fradette, J., Pouliot, R. (2019) Modulation of the Lipid Profile of Reconstructed Skin Substitutes after Essential Fatty Acid Supplementation Affects Testosterone Permeability. Cells. 8, 1142; doi:10.3390/cells8101142.
  • Lorthois, I., Simard, M., Morin, S. et Pouliot, R. (2019) Infiltration of T cells into a three-dimensional psoriatic skin model mimics pathological key features. International Journal of Molecular Sciences. 20, 1670; doi:10.3390/ijms20071670 .
  • Morin, A., Simard, M., Rioux, G., Grenier, A., Morin, S. et Pouliot, R. (2019) Application of an In Vitro Psoriatic Skin Model to Study Cutaneous Metabolization of Tazarotene Processes, 7, 871; doi:10.3390/pr7120871.
  • Rioux, G., Pouliot-Bé́rubé́, C., Simard, M., Benhassine, M., Soucy, J., Gué́rin, S.L. et Pouliot, R. (2018) The tissue-engineered human psoriatic skin substitute: a valuable in vitro model to identify genes with altered expression in lesional psoriasis. International Journal of Molecular Sciences. 19, 2923; doi:10.3390/ijms19102923.
  • Lorthois, I. et Pouliot, R. (2017) Contribution of in vivo and organotypic 3D models to understanding the role of macrophages and neutrophils in the pathogenesis of psoriasis. Mediators of Inflammation. 2017: 1-13.
  • Angers, L., Dubois Declercq, S., Masson1, L.-C., Roy, B., Jean, J., Morin, A. and Pouliot, R. (2017), Effects of Freezing on Functionality and Physicochemical Properties of A 3D-Human Skin Model. Journal of Dermatology & Cosmetology, 1(2): 00007. DOI: 10.15406/jdc.2017.01.00007.
  • Duque-Fernandez, A., Gauthier, L., Simard, M., Jean, J., Gendreau, I., Morin, A., ... and Pouliot, R. (2016), A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions. Biochemistry and Biophysics Reports, 8, 268-276.
  • Pouliot-Bérubé, C., Zaniolo, K., Guérin, S.L. and Pouliot, R. (2016), Tissue-engineered human psoriatic skin supplemented with cytokines as an in vitro model to study psoriasis, Regenerative Medecine, sous presse.
  • Bélanger, A., Padilha de Oliveira, C., Maheux, M. and Pouliot, R. (2016), Plaque psoriasis : Understanding risk factors of this inflammatory skin pathology. Journal of Cosmetics, Dermatological Sciences and Applications, 6, 67-80.
  • Chabaud, S., Simard, M., Gendreau, I., Pouliot, R. and Bolduc, S. (2016), Origin of serum affects quality of engineered tissues produced by the self-assembly approach. Scientifica, Article ID 3825645, 10 pages.
  • Paré, B., Deschênes, L.T., Pouliot, R., Dupré, N. and Gros-Louis, F. (2016), An optimized approach to recover secreted proteins from fibroblast conditioned-media for secretomic analysis. Frontiers in Cellular Neuroscience, 10, 70.
  • Leroy, M., Lefevre, T., Pouliot, R., Auger, M., Laroche, G. (2015), Using infrared and Raman microspectroscopies to compare ex vivo involved psoriatic skin with normal human skin. Journal of Biomedical Optics, 20, 6, 067004.
  • Jean, J., Leroy, M., Duque-Fernandez, A., Bernard, G., Soucy, J. and Pouliot, R. (2015), Characterization of a psoriatic skin model produced with involved or uninvolved cells. Journal of Tissue Engineering and Regenerative Medecine, 9, 7, 789-798.
  • Ayata, E., Auger, M. et Pouliot, R. (2015) Behaviour of endothelial cells in a tridimensional in vitro environment. Biomedical research international, 1-9.
    Résumé
  • Ayata, E., Auger, M. et Pouliot, R. (2014) Study of in vitro capillary-like structures in psoriatic skin substitutes. BioResearch Open Access, 3, 5, 197-205.
  • Leroy, M., Labbé, J-F., Jean, J., Ouellet, M., Robert, é., Lefèvre, T., Pézolet, M., Soucy, J., Auger, M. et Pouliot, R. (2014) A comparative study between human skin substitutes and human skin using Raman microspectroscopy Acta Biomaterialia. Acta Biomaterialia, 10, 2703-2711.
  • Garcia-Pérez, M-E., Allayes, I., Rusu, D., Pouliot, R., Janezic, T. S. et Poubelle, P-E. (2013), Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-α-activated psoriatic keratinocytes. Impact on NF-κB pathway. Journal of Ethnopharmacology, 151, 265-278.
    Résumé
  • Guérard, S., Allaeys, I., Martin, G., Pouliot, R. et Poubelle, P. (2013), Psoriatic keratinocytes prime neutrophils for an overproduction of superoxide anions. Archive in Dermatology Research, DOI:10.1007/s00403-013-1404-z.
  • Leroy, M., Auger, M., Laroche, G. et Pouliot, R. (2013), Characterizing the structure of human skin substitutes by infrared microspectroscopy imaging. Analytical and Bioanalytical Chemistry, DOI:10.1007/s00216-013-7103-y.
  • Dubois-Declercq, S. et Pouliot, R. (2013), Promising new treatments for psoriasis. Dermatology section of The Scientific World Journal.
    Résumé
  • Lavoie, A., Fugère, C., Beauparlant, A., Goyer, B., Larouche, D., Paquet, C., Desgagné, M., Sauvé, S., Robitaille, H., Dunnwald, M. Kim, D. H., Pouliot, R., Fradette, J. et Germain, L., (2013), Human epithelial stem cells persist within tissue-engineered skin produced by the self-assembly approach. Tissue Engineering, DOI:10.1089/ten.TEA.2012.0117.


  • Garcia-Pérez, M-E., Royer, M., Herbette, G., Desjardins, Y., Pouliot, R. et Stevanovic, T. (2012), Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. Food Chemistry.
    Résumé
  • Martin, G., Guérard, S., Fortin, M-M., Rusu, D., Soucy, J., Poubelle, P-E. et Pouliot, R. (2012), The in vitro pathological crosstalk between T lymphocytes and keratinocytes in psoriasis. Laboratory Investigation, 1-13.
    Résumé
  • Guérard, S. et Pouliot, R. (2012), The role of angiogenesis in the pathogenesis of psoriasis: mechanisms and clinical implications. Journal of Clinical and Experimental Dermatology Research, S:4.
    Résumé
  • Garcia-Pérez, M-E., Jean, J. et Pouliot, R. (2012), Antipsoriatic Drug Development: Challenges and New Emerging Therapies. Recent Patents on Inflammation & Allergy Drug Discovery, 6: 3-21.
    Résumé
  • Jean, J., Garcia-Pérez, M-E. et Pouliot, R. (2011), Bioengineered Skin: the Self-assembly Approach. Journal of Tissue Science and Engineering, S:5.
    Résumé
  • Jean, J., Soucy, J. et Pouliot, R. (2011), Effects of retinoic acid on keratinocyte proliferation and differentiation in a psoriatic skin model. Tissue Engineering Part A, 13-14: 1859-1868.
    Résumé
  • Jean, J., Bernard, G., Duque-Fernandez, A., Soucy, J., Auger, F.A. et Pouliot, R. (2011), Effects of serum-free culture at the air-liquid interface in a human tissue-engineered skin substitute. Tissue Engineering Part A, 7-8: 877-888.
    Résumé
  • Garcia-Pérez, M-E., Royer, M., Duque-Fernandez, A., Diouf, P., Stevanovic, T. et Pouliot, R. (2010), Antioxidant, toxicological and antiproliferative properties of Canadian polyphenolic extracts on normal and psoriatic keratinocytes. Journal of Ethnopharmacology, 132(1) : 251-258.
    Résumé
  • Rosa-Fortin, M-M., Poubelle, P-E., Soucy, J. et Pouliot, R. (2010), Cellular interactions in vitro: psoriatic keratinocytes enhance lymphocyte survival. Psoriasis Forum, 16(1): 12-15.
    Résumé
  • Jean, J., Lapointe, M., Soucy, J. et Pouliot, R. (2009), Development of an in vitro psoriatic skin model by tissue engineering. Journal of Dermatological Science, 53(1): 19-25.
    Résumé
  • Bernard, G., Auger, M., Soucy, J. et Pouliot, R., (2007), Physical characterization of the stratum corneum of an in vitro psoriatic skin model by ATR-FTIR and Raman spectroscopies. Biochimica and Biophysica Acta, 1770: 1317-1323.
    Résumé
Livre publié
  • Jean, J., Garcia-Pérez, M-E., Guérard, S. et Pouliot, R. (2011), "Psoriasis : Causes, Treatments and Pathological Models". Éditeurs: Nova Science Publishers. ISBN-10: 1612096913
    Résumé
Chapitres de livres publiés
  • Roy, B., Simard, M., Lorthois, I., Bélanger, A., Maheux, M., Duque-Fernandez, A., Rioux, G., Simard, P., Deslauriers, M., Masson, L.-C., Morin, A. and Pouliot, R., "In vitro models of Psoriasis", Elsevier, Skin Tissue Models (IN-PRESS).
  • Simard, M., Lorthois, L., Maheux, M., Roy, B., Masson, L.-C., Morin, A. and Pouliot, R. (2016). "Reconstructed skin models for clinical and fundamental applications", Nova Biomedical, Advances in medicine and biology, vol. 102, pp. 197-217.
  • Jean, J., Angers, L., Gendreau, I. and Pouliot, R. (2013), "Pigmented skin models: Understand the mechanisms of melanocytes", dans: Regenerative Medecine and Tissue Engineering. Éditeur: Jose A. Andrades, In Tech Publishers, Chap. 30 pp. 759-785.
  • Jean, J., Garcia-Pérez, M-E. and Pouliot, R. (2011), "Psoriatic Skin Models: A Need for the Pharmaceutical Industry" dans: Psoriasis. Éditeur : Jennifer Soung, InTech Publishers, Chap. 4, pp 47-62.
    Résumé
  • Jean, J., Garcia-Pérez, M.-E., Guérard, S. and Pouliot, R. (2011), "Current knowledge in psoriasis: an overview of the skin disease" dans: Psoriasis: causes, diagnosis and treatment. Éditeurs: Julian A. Carrasco, Nova Science Publishers, Chap.2, pp 63-104.
    Résumé
  • Berthod, F. Germain, L. Pouliot, R. and Auger, F.A. (2010), "How to achieve early vascularization of tissue-engineered skin substitutes" dans: Advances in wound care, translational medicine: from benchtop to bedside to community and back. Éditeurs: Sen, C.K., Comprehensive Wound Center The Ohio State University Medical Center Columbus, Ohio, Chap. 72, pp 445-450.
    Résumé
  • Larouche, D., Jean, J., Berthod, F. Germain, L. and Pouliot, R. (2010) "Markers for an in vitro skin substitute" dans: Alternative technologies to animal testing, Methods in bioengineering series. Éditeurs: Maguire, T. and Novik, E., Chap. 11, pp183-203.
    Résumé
  • Jean, J. and Pouliot, R. (2010), "In vivo and in vitro models of psoriasis" dans: Tissue engineering. Éditeur: Eberli, D., Chap. 18, pp 359-382.
    Résumé
Articles promotionnels des projets de recherche
  • Pouliot, R. (2014), Modelling psoriasis. International Innovation, Healthcare Issue, 122, 95-97.
  • Pouliot, R. et Auger, M., (2012), The reconstruction of psoriatic skin. International Innovation, Healthcare Issue, 16, 76-78.